Historic and DNA evidence suggests that the George May family has its roots in several European countries before settling in America.  It is likely that the family was originally from Scotland, immigrated to Ireland for several generations, and then eventually immigrated to America in the mid to late 1700s.

The May Family may have connections to Germany in that the Scots-Irish and Germans immigrated to America around the same time, settled in both Pennsylvania and Virginia and possibly lived in the same communities and intermarried.